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Monthly Archives: September 2013

EUS for Neuroendocrine Tumors

Depending on who you are and how you count, there are almost twenty kinds of pancreatic cancer. The main two that we generally speak of are ductal adenocarcinoma of the pancreas which arises from the non-hormonal part of the organ and may be responsible for as much as 85% of cases, and pancreatic neuroendocrine tumors […]

IA and IV Gemcitabine plus Mitomycin-C for Pancreatic Cancer

Recent advances over the drug agent gemcitabine for advanced pancreatic cancer (ductal adenocarcinoma of the pancreas) are still in progress but the current strong regimins for first-line therapy appear to include the FOLFIRINOX (5-FU based) combination regimen, and now recently Abraxane plus gemcitabine. Now comes a study by German researchers Lorenz and colleagues from the […]

FDA Approval: Nab-paclitaxel in Combination with Gemcitabine for Pancreatic Cancer

On September 6th the U.S Food and Drug Administration (FDA) – per its commendable fast track expedited review program for “orphan” diseases (which now includes pancreatic cancer) has approved nab-paclitaxel (trade name: Abraxane) for use in in combination with gemcitabine for metastatic pancreatic cancer (ductal adenocarcinoma of the pancreas). The previous drug agent officially approved […]

Chemotherapy Regimen for NET: Platinum Agent Plus Topoisomerase Inhibitor

The exploration of chemotherapy for advanced pancreatic neuroendocrine tumors has been somewhat sparse, but has increased pace during the past few years. Certain of these regimens have met with some success, increasing the armamentarium of clinicians. Beijing, China researchers led by Shen from the Peking University School of Oncology have published an article in the […]

Heavy-duty Multimodal Therapy with RFA for Locally Advanced Pancreatic Cancer

In some ways, both early stage and late stage pancreatic cancer (under current thinking paradigms) may be easier stages in which to offer standard care: early receives surgery (without or without neoadjuvant or adjuvant augmentation), and late stage is typically chemotherapy in one combination or another – at least initially involving either gemcitabine or 5-FU.  […]