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Monthly Archives: January 2014

Results in on Double Punch Vaccine: Why the FDA Granted Orphan Status to CRS-207 + GVAX in Pancreatic Cancer

A quick note related to an earlier Pancreatica blog posting from October 24, 2013. At the 2014 Gastrointestinal Cancers Symposium in San Francisco (January 16-18) as hosted by the American Society of Clinical Oncology (ASCO), the results of an interesting vaccine study for pancreatic cancer (ductal adenocarcinoma of the pancreas) were released. By way of background […]

MiRNA Panels for the Diagnosis of Pancreatic Cancer ?

A majority of cases of pancreatic cancer (ductal adenocarcinoma of the pancreas) are diagnosed in advanced stage. The main reason is that early stage disease tends to have no symptoms, or vague symptoms.  And there is no good screening test for early pancreatic cancer, or a simple diagnostic indicator.  The two biomarkers most often used with […]

Inhibiting the Effects of the Most Common Mutated Oncogene in Pancreatic Cancer

The K-Ras gene is found to be mutated in 30% of all tumors (human), but this rises to 90% or more in pancreatic cancer (ductal adenocarcinoma of the pancreas). It is considered an “oncogene” meaning a gene whose mutation typically initiates a cascade of proteins that signal for rapid cell growth and division – in […]

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