Map of Pancreatica Walks and Runs

Category Archives: Medical Research

Inhibiting the Effects of the Most Common Mutated Oncogene in Pancreatic Cancer

The K-Ras gene is found to be mutated in 30% of all tumors (human), but this rises to 90% or more in pancreatic adenocarcinoma. It is considered an “oncogene” meaning a gene whose mutation typically initiates a cascade of proteins that signal for rapid cell growth and division – in this case by promoting an […]

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Lymph Node Surgery for NETs ?

Hawkins and colleagues at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, Missouri E-published an article on November 19, 2013 in the journal Annals of Surgery  which examined regional lymph node status and the medical disposition of 136 of their patients who had received surgery for pancreatic neuroendocrine tumors from 1994 through […]

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Penetrating the Stroma: Plerixafor Inhibits Chemokine Ligand 12 (of CXCR4) Allowing for Enhanced Biological Therapy in Adenocarcinoma of the Pancreas

The physical size of the structural aspect of pancreatic adenocarcinoma can be misleading as perhaps 90% of the tumor bulk is actually the somewhat inert – and not completely understood – stromal tissue that the “surrounds” the malignant aspect of pancreatic cancer. One practical effect of the stromal tissue is that it may physically, through […]

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