Map of Pancreatica Walks and Runs

Category Archives: Pancreatic Cancer Medical Treatment

“Modified” FOLFIRINOX Regimen Approved by FDA for 2nd Line Treatment of Pancreatic Cancer

On the 22nd of October, 2015, the U.S. Food and Drug Administration approved a new combination therapy that includes the drug Onivyde for patients with metastatic pancreatic cancer who had earlier been treated until progression of disease while on gemcitabine or a gemcitabine-based regimen. Onivyde is liposomal irinotecan, a topoisomerase I inhibitor (was called CPT-11, […]

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Clinical trial of Combination of Targeted Anti-Kras Therapy for Pancreatic Cancer

Dutch and primarily other European researchers are about to begin a human clinical trial involving a regimen of two relatively new targeted therapies (afatinib plus selumetinib) for the treatment of pancreatic cancer.  Afatinib is known as Gilotrif in the U.S., and is produced by the family-owned global but German-headquartered Boehringer Ingelheim Pharmaceuticals firm.  Selumetinib is […]

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Hedgehog Pathway Inhibition Slows Pancreatic Cancer Cell Growth

You may wonder what this has to do with pancreatic cancer, but please know that those of us who are old enough to remember once shivered and screamed in horror at the 1958 move, The Fly, whereby the protagonist ended up half human, half housefly (musca domestica).  This fear may not be too far from […]

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