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Category Archives: Pancreatic Cancer

Biomarker miR-10b for Cancer of the Pancreas: earlier diagnosis and/or therapeutic target?

As alluded to in another recent blog entry, the study of microRNA has been a source of great interest as to the possible development of biomarkers that may screen or aid on the diagnosis of pancreatic cancer.  MicroRNAs (or sometimes abbreviated miR) are small (18 to 25 nucleotide) non-coding RNA molecules that are involved in […]

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SOX Chemo Regimen as 2nd Line for Cancer of the Pancreas

Acronyms in medicine are often a hoot.  We have the four-drug combination called FOLFIRINOX.  Recently, here at Pancreatica we reported on a study of a three-drug version of the above termed: OFF.   Now comes a review of the regimen of S-1 plus oxaliplatin by Japanese researchers, which combination they term: SOX.  In a sense SOX […]

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DNA Epigenetic Changes for the Earlier Diagnosis of Cancer of the Pancreas

In an absolutely remarkable, fascinating and possible game-changing study, Joo Mi Yi and Nita Ahuja and colleagues (primarily) from Johns Hopkins University have identified a “panel” of biomarkers based on DNA methylation of two relatively obscure genes (that can be identified in serum) for use, at least at an experimental level at this stage, for […]

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