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Confronting Pancreatic Cancer

Neuroendocrine Tumors
Information on islet-cell and carcinoid cancers including recent study results, types and active clinical trials

Neuroendocrine Clinical Trials

Pancreatica Trial ID Trial Name Trial Phase Trial Location

       
       
PA-6768 Phase II Study of CPT-11 in Patients with Metastatic, Unresectable Carcinoid Tumors or Islet Cell Carcinoma. Phase 2 Houston, TX, US
       
PA-6957 Phase II Study of Paclitaxel, Carboplatin and Oral Etoposide Followed by Weekly Paclitaxel in the Treatment of High-grade Neuroendocrine Carcinoma. Phase 2 Huntsville, AL, US
Nashville, TN, US
       
PA-7206 Phase I Pilot Study of Flavopiridol in Patients With Locally Advanced or Metastatic Neuroendocrine Tumors. Phase 1 Columbus, OH, US
       
PA-7298 Phase I/II Pilot Study of Fluorouracil, Leucovorin Calcium, and Oxaliplatin (FOLFOX) With Bevacizumab in Patients With Advanced Neuroendocrine Tumors. Phase 1 / 2 San Francisco, CA, US
       
PA-7367 Phase II Study of Capecitabine and Temozolomide For Progressive, Differentiated, Metastatic Neuroendocrine Cancers. Phase 2 New York, NY, US
       
PA-7537 High Dose Indium-111 Pentetreotide Therapy in Somatostatin Receptor Expressing Neuroendocrine Neoplasms. Phase 3 Houston, TX, US
       
PA-7538 Study to Investigate the Antiproliferative Effect of Octreotide in Patients With Metastasized Neuroendocrine Tumors of the Midgut. Phase 3 Marburg, Germany
       
PA-7539 Study of Lanreotide Autogel in Non-Functioning Entero-Pancreatic Endocrine Tumours. Phase 3 Vienna, Austria
Prague, Czech Republic
Arhus, Denmark
Belfast, Ireland
Cardiff, England
Edinburgh, England
Glasgow , England
Leeds , England
Leicester , England
London, England
Nottingham, England
Sheffield, England
Clichy, France
Lille , France
Marseille, France
Reims, France
Villejuif , France
Bologna, Italy
Milan, Italy
Zabrze, Poland
Barcelona, Spain
       
PA-7540 A Randomized, Double-Blind Placebo-Controlled, Multicenter Phase III Study in Patients With Advanced Carcinoid Tumor Receiving Octreotide Depot and Everolimus 10 mg/Day or Octreotide Depot and Placebo. Phase 3 Fayetteville, AR, US
Little Rock , AR, US
Tucson, AZ, US
Anaheim, CA, US
Los Angeles, CA, US
Aurora, CO, US
Denver, CO, US
Norwich, CT, US
Southington, CT, US
Stamford , CT, US
Ocala, FL, US
Tampa, FL, US
Iowa City, IA, US
Arlington Heights, IL, US
Indianapolis, IN, US
Terry Asher, IN, US
Kansas City, KS, US
Overland Park, KS, US
Louisville, KY, US
Kenner, LA, US
Rochester, MN, US
St. Louis, MO, US
Durham, NC, US
Lebanon, NH, US
Albany, NY, US
New York, NY, US
Cleveland, OH, US
Kettering, OH, US
Philadelphia, PA, US
Charleston, SC, US
Greenville, SC, US
Nashville, TN, US
Austin, TX, US
Corpus Christi, TX, US
Dallas, TX, US
Fort Worth, TX, US
Houston, TX, US
Temple, TX, US
Tyler, TX, US
Norfolk, VA, US
Vancouver, WA, US
Madison, WI, US
Heidelberg, Australia
Herston, Australia
Woodville, Australia
       
PA-7541 Phase I/II Study of BB-10901 in Patients With Recurrent or Refractory Small Cell Lung Cancer, CD56-Positive Small Cell Carcinoma of Unknown Origin, Other Pulmonary Tumors of Neuroendocrine Origin, Non-Pulmonary Small Cell Carcinoma, Metastatic Carcinoid Tumor, or Other CD56+ Solid Tumors (Phase I portion completed; patients with refractory small cell lung cancer, other pulmonary tumors of neuroendocrine origin, CD56-negative non-pulmonary small cell carcinomas, metastatic carcinoid tumors, or other CD56+ solid tumors are no longer being accrued as of 10/19/2005). Phase 2 Denver, CO, US
Ocoee , FL, US
Springfield, MA, US
Albany, NY, US
Columbus, OH, US
Kettering, OH, US
Greenville, SC, US
Houston, TX, US
Tyler, TX, US
Norfolk , VA, US
Vancouver, WA, US
       
PA-7549 Irinotecan and Cisplatin for High Grade Neuroendocrine Carcinoma of the Gastrointestinal Tract. Phase 2 Houston, TX, US
       
PA-7551 Phase II Capecitabine, Oxaliplatin & Bevacizumab for Metastatic / Unresectable Neuroendocrine Tumors. Phase 2 Stanford, CA, US
       
PA-7553 Phase II Study of Pazopanib Hydrochloride in Patients With Low- or Intermediate-Grade Advanced Neuroendocrine Carcinoma. Phase 2 Boston, MA, US
Houston, TX, US
       
PA-7554 An Open Label Study to Evaluate the Effect of Avastin in Association With Chemotherapy on Progression-Free Survival in Patients With Progressive Advanced/Metastatic Well-Differentiated Digestive Endocrine Tumors of the Gastrointestinal Tract. Phase 2 Angers, France
Bordeaux , France
Boulogne-Billancourt, France
Caen, France
Cambray-Les-Tours, France
Clichy, France
Dijon, France
Lille, France
Lyon, France
Marseille, France
Montpellier, France
Paris, France
Poitiers, France
Reims, France
Saint Breieuc, France
Strasbourg, France
Toulouse, France
Villejuif, France
       
PA-7558 Phase I Study of BB-10901 in Patients With Relapsed or Refractory Small Cell Lung Cancer, Other Pulmonary Tumors of Neuroendocrine Origin, Non-Pulmonary Small Cell Carcinoma, Metastatic Carcinoid Tumors, or Other CD56-Positive Solid Tumors. Phase 1 Springfield, MA, US
Houston, TX, US
Manchester , England
Sheffield, England
Sutton, Surrey, England
       
PA-7560 Effectiveness of Octreotide in Patients With Metastasized Neuroendocrine Tumors of the Midgut. Phase 3 Marburg, Germany
       
PA-7561 Prospective Evaluation Study of Tumor Angiogenesis in Patients With Endocrine Neoplasms. Unspecified Bethesda, MD, US
       
PA-7563 Phase 1-2 Study of Iobenguane (MIBG) I 131 in Patients With Malignant Pheochromocytoma/Paraganglioma. Phase 2 Durham, NC, US
New York , NY, US
Providence, RI, US
       
PA-7564 A Study Of Sunitinib Compared To Placebo For Patients With Advanced Pancreatic Islet Cell Tumors. Phase 3 Iowa City, IA, US
Jeffersonville , IN, US
Louisville, KY, US
Shelbyville, KY, US
Worcester, MA, US
St. Peters, MO, US
Creve Coeur, MO, US
St Louis , MO, US
Austin, TX, US
Georgetown, TX, US
Norfolk, VA, US
Redcliffe, Queensland, Australia
Kogarah, New South Wales, Australia
Perth, Western Australia, Australia
Brussels, Belgium
Halifax, Nova Scotia, Canada
Toronto, Ontario, Canada
Vancouver, British Columbia, Canada
Montreal, QC, Canada
Santafe de Bogota, Colombia
Liverpool, England
Bordeaux , France
Clichy Cedex, France
Lyon, France
Marseille, France
Paris, France
Heidelberg, Germany
Luebeck, Germany
Bad Berka, Germany
Berlin, Germany
Ulm, Germany
Rozzano , Italy
Barcelona, Spain
Madrid, Spain
Navarra, Spain
       
PA-7588 Phase II Study of Sunitinib Malate Following Hepatic Artery Embolization for Metastatic Gastrointestinal Neuroendocrine Tumors. Phase 2 Tampa, FL, US
       
PA-7680 A Randomized Double-Blind Phase III Study of RAD001 10 mg/d Plus Best Supportive Care Versus Placebo Plus Best Supportive Care in the Treatment of Patients With Advanced Pancreatic Neuroendocrine Tumor (NET). Phase 3 Mobile, AL, US
Anaheim, CA, US
Los Angeles, CA, US
San Francisco, CA, US
Denver, CO, US
Iowa City, IA, US
Indianapolis, IN, US
Louisville , KY, US
Rochester, MN, US
Charlotte, NC, US
Littleton, NH, US
Morristown, NJ, US
Columbus, OH, US
Portland, OR, US
Bethlehem, PA, US
Philadelphia, PA, US
Fort Worth, TX, US
Houston, TX, US
       
PA-7681 Safety and Efficacy Study of PTK787/ZK222584 to Treat Metastatic Neuroendocrine Tumors. Phase 2 Kenner , LA, US
       
PA-7723 Efficacy Study of Sorafenib and Cyclophosphamide to Treat Neuroendocrine Tumors. Phase 2 Toronto, ON, Canada
       
PA-7724 Exploratory Study of Avastin (Bevacizumab) and RAD001 (Everolimus) in Advanced Low or Intermediate Grade Neuroendocrine Carcinoma. Phase 2 Houston, TX, US
       
PA-7725 A Phase I Trial of the mTOR Inhibitor RAD001 in Combination With VEGF Receptor Tyrosine Kinase Inhibitor PTK787/ZK 222584 in Patients With Advanced Solid Tumors. Phase 1 Rochester, MN, US
       
PA-7726 An Open Lable Phase II Study Evaluating the Safety and Efficacy of PTK787/ZK222584 in Patients With Metastatic Neuroendocrine Tumors That Have Evidence of Progressive Disease or an Increase in Disease Related Syndrome Symptoms. Phase 2 Iowa City, IA, US
       
PA-7735 A Phase II Clinical and Biological Study of Lithium Carbonate in Patients With Low-Grade Neuroendocrine Tumors. Phase 2 Madison, WI, US
       
PA-7736 Octreotide and Interferon Alfa-2b or Bevacizumab in Treating Patients With Metastatic or Locally Advanced, High-Risk Neuroendocrine Tumor. Phase 3 Mobile, AL, US
Fort Smith, AR, US
Los Angeles, CA, US
San Diego, CA, US
Washington, DC, US
Peoria, IL, US
Baltimore, MD, US

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