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WHY US? BECAUSE EARLY DIAGNOSIS IS KEY

Currently, only about 15% of those diagnosed with pancreatic cancer are eligible for potentially curative surgery. We need to find the disease earlier!

Pancreatic cancer is very aggressive. Fortunately together, so are we.

We are dedicated to promoting awareness, increasing education, and furthering pancreatic cancer research.

THE PANCREAS

The pancreas is a small, spongy organ of about six inches long which lies just under the curvature of the stomach on the left side and deep within the abdomen. The function of the pancreas is a complicated, but one could say that it primarily does two things. It produces enzymes which are useful for the digestion of food AND it secretes hormones which, among other things, help maintain and regulate body sugar levels.

The pancreatic enzymes are produced in cells which are called acinar cells; this part of the pancreas is called the EXOCRINE part of the pancreas. The clumps of acinar cells are found gathered throughout the pancreas; these cells release salts and enzymes into small tributaries which collect and transport this pancreatic fluid (called “pancreatic juice”). These small creeks eventually gather and coalesce into the river known as the pancreatic duct. This sixteenth-of-an inch-wide duct runs from left-to-right along the length of the pancreas, eventually (usually) joining up with the bile duct and emptying its combined digestive contents into the first part of the small bowel (called the duodenum). These enzyme-carrying fluids from the bile and pancreatic ducts are necessary for efficient digestion.

Additionally, the pancreas has an ENDOCRINE or hormonal function. For example, inside of specialized groupings of cells called the Islets of Langerhans, the pancreas produces hormones which are secreted directly into the blood stream. These hormones have numerous effects, and will be addressed in a simplistic fashion here. Insulin (produced by so-called beta cells) has effects, among which it lowers the level of glucose in the blood. Glucagon (produced by alpha cells) tends to increase the level of blood sugar. Other hormones, as well as various peptides, are produced by the endocrine pancreas–including also somatostatin, a hormone which inhibits the secretion of insulin. The hormones produced by the pancreas are necessary for the healthy regulation of human physiology.

Thus, the pancreas is a small but critical organ for an individual’s well-being.

Our science board is composed of:

James Abbruzzese, MD Chief, Medical Oncology Duke University

Markus Büchler, MD Chairman, Surgery Heidelberg University, Germany

Ralph Hruban, MD Director, GI / Liver Pathology Johns Hopkins University

Eileen O’Reilly, MD Associate Director for Clinical Research – Memorial Sloan-Kettering Cancer Center

Margaret Tempero, MD Chief, Medical Oncology University of California at San Francisco

Our Philosophy About Pancreatic Cancer

Pancreatic cancer is a serious disease. Taking an aggressive rational stance at the earliest possible time, supported by the best medical team, and treated in the most appropriate manner gives the best chance for survival.

We believe in strong patient-physician bonds, scientifically-based treatment, and that comfort can come from knowing that everything that reasonably can be done – is being done.

That the best approach is meeting cancer of the pancreas head-on and armed with the best available information.

Cancer Patients Alliance is a 501(c)(3) non-profit. Initiatives include, ToFightCancer.com and Pancreatica.org. All Donations are tax-deductible. Pancreatic cancer is the least funded cancer in terms of research.

Despite causing enormous mortality, pancreatic cancer receives (on a mortality basis) much less funding for research than most of the other major cancers. Currently, there is no molecular marker or genetic screening tool to aid in the earlier diagnosis or screening of pancreatic cancer. Treatment results would improve significantly if this cancer could be diagnosed at an earlier stage.

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Our mission is to promote awareness, increase education, and further pancreatic cancer research, specifically research aimed at early diagnosis.

Early diagnosis is key:
Survival increases dramatically if patients are diagnosed in time for surgery!

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Pancreatic cancer is expected to become the 2nd leading cause of cancer-related death by the year 2020

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