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Monthly Archives: December 2013

Plerixafor Inhibits Chemokine Ligand 12 (of CXCR4): Biological Therapy in Pancreatic Cancer

The physical size of the structural aspect of pancreatic cancer (ductal adenocarcinoma of the pancreas) can be misleading as perhaps 90% of the tumor bulk is actually the somewhat inert – and not completely understood – stromal tissue that the “surrounds” the malignant aspect of pancreatic cancer. One practical effect of the stromal tissue is […]

Do Women Respond More Favorably Than Men to the FOLFIRINOX Regimen in Advanced Pancreatic Cancer ?

We have come across an interesting recent finding from researchers in Austria. Greil and colleagues from the Paracelsus Medical University in Salzburg, have published the results of their work in the January 2014 issue of the International Journal of Oncology. These findings appear to suggest that the female gender may be a predictor of a […]

Is CA125 a Better Marker than CA 19-9 for Resectability in Pancreatic Cancer ?

Color this finding: curious (and consequently interesting). Chinese researchers in Shanghai including Yu and colleagues at Fudan University published recent research findings in the December 2013 issue of the Journal of Gastrointestinal Surgery, the official periodical of the Society for Surgery of the Alimentary Tract.  They reviewed the results of a number of potential serum […]

Salivary Fluid Markers for Pancreatic Cancer: the evidence mounts

However counterintuitive, the association between saliva and the dental environment AND pancreatic cancer (ductal adenocarcinoma of the pancreas) continues to garner highly interesting research.  One team lead by David T. Wong and colleagues at the Dental Research Institute of the UCLA School of Dentistry in Los Angeles, California first came to our attention per the […]

Prolonged Duration of Neoadjuvant Treatment May Confer Big Benefits in Pancreatic Cancer

The move away from surgical diagnosis to radiographic criteria in many and now even most efforts at the staging of pancreatic cancer (ductal adenocarcinoma of the pancreas) carries a number of somewhat unspoken but profound consequences, one being efforts to find ways to downstage the diagnosis so as to profitably utilize surgery in locally advanced […]