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Author Archives: pancreatica

Neoadjuvant Therapy in Stage 3 Pancreatic Cancer Confers Survival Advantage

In a certain sense, treatment selection by professionals is easier in early or late stage pancreatic cancer (ductal adenocarcinoma of the pancreas) because the options tend to be narrower: early yields surgery; late leans toward chemotherapy alone. The middle stages II and III, or locally advanced, potentially resectable pancreatic cancer, etc. tend to be more […]

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Later Surgery for Advanced Pancreatic Cancer in Treatment Responders with Hepatic Lesions ?

Criteria for exclusion of patients from surgery for pancreatic cancer (ductal adenocarcinoma of the pancreas) include detection of distal metastases including those noted in the liver (also known as the hepatic organ).  However especially over the past decade, there have been a number of studies aimed at trying to discern whether liver lesions alone should […]

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How many Patients with Pancreatic Cancer are Platinum Responders ?

Here in the Pancreatica Blog we have reported previous studies documenting patients with pancreatic cancer (ductal adenocarcinoma of the pancreas) with specific genetic characteristics such BRCA1 and BRCA2 mutations who have demonstrated robust treatment responses to DNA crosslinking agent “chemotherapy” such as platinum salts, PARP [poly ADP-ribose polymerase enzyme] inhibitors, and others.  By way of […]

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