Author Archives: pancreatica
DNA Found in Exosomes in Pancreatic Cancer – with Characteristic Mutations !
We recently commented (here) on the interesting properties of exosomes that were explored as possible messengers within the body including saliva in the context specifically of biomarkers in pancreatic cancer (ductal adenocarcinoma of the pancreas) by Wong and dental colleagues at UCLA. Exosomes are tiny bubble type structures found in most biological fluids that contain […]
Engineered Nano-delivery of Gemcitabine for Pancreatic Cancer (in Mice)
Normally, we do not address pre-clinical studies for pancreatic cancer (ductal adenocarcinoma of the pancreas) in the Pancreatica Blog as so many of these fail when finally subjected to human testing. But sometimes there are such studies that are so intriguing that they cannot be easily ignored. And this particular research study of nanotherapy for […]
Results in on Double Punch Vaccine: Why the FDA Granted Orphan Status to CRS-207 + GVAX in Pancreatic Cancer
A quick note related to an earlier Pancreatica blog posting from October 24, 2013. At the 2014 Gastrointestinal Cancers Symposium in San Francisco (January 16-18) as hosted by the American Society of Clinical Oncology (ASCO), the results of an interesting vaccine study for pancreatic cancer (ductal adenocarcinoma of the pancreas) were released. By way of background […]
MiRNA Panels for the Diagnosis of Pancreatic Cancer ?
A majority of cases of pancreatic cancer (ductal adenocarcinoma of the pancreas) are diagnosed in advanced stage. The main reason is that early stage disease tends to have no symptoms, or vague symptoms. And there is no good screening test for early pancreatic cancer, or a simple diagnostic indicator. The two biomarkers most often used with […]
Inhibiting the Effects of the Most Common Mutated Oncogene in Pancreatic Cancer
The K-Ras gene is found to be mutated in 30% of all tumors (human), but this rises to 90% or more in pancreatic cancer (ductal adenocarcinoma of the pancreas). It is considered an “oncogene” meaning a gene whose mutation typically initiates a cascade of proteins that signal for rapid cell growth and division – in […]