Author Archives: pancreatica
Inhibiting the Effects of the Most Common Mutated Oncogene in Pancreatic Cancer
The K-Ras gene is found to be mutated in 30% of all tumors (human), but this rises to 90% or more in pancreatic cancer (ductal adenocarcinoma of the pancreas). It is considered an “oncogene” meaning a gene whose mutation typically initiates a cascade of proteins that signal for rapid cell growth and division – in […]
Lymph Node Surgery for Neuroendocrine Tumors ?
Hawkins and colleagues at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, Missouri E-published an article on November 19, 2013 in the journal Annals of Surgery which examined regional lymph node status and the medical disposition of 136 of their patients who had received surgery for pancreatic neuroendocrine tumors from 1994 through […]
Plerixafor Inhibits Chemokine Ligand 12 (of CXCR4): Biological Therapy in Pancreatic Cancer
The physical size of the structural aspect of pancreatic cancer (ductal adenocarcinoma of the pancreas) can be misleading as perhaps 90% of the tumor bulk is actually the somewhat inert – and not completely understood – stromal tissue that the “surrounds” the malignant aspect of pancreatic cancer. One practical effect of the stromal tissue is […]
Do Women Respond More Favorably Than Men to the FOLFIRINOX Regimen in Advanced Pancreatic Cancer ?
We have come across an interesting recent finding from researchers in Austria. Greil and colleagues from the Paracelsus Medical University in Salzburg, have published the results of their work in the January 2014 issue of the International Journal of Oncology. These findings appear to suggest that the female gender may be a predictor of a […]
Is CA125 a Better Marker than CA 19-9 for Resectability in Pancreatic Cancer ?
Color this finding: curious (and consequently interesting). Chinese researchers in Shanghai including Yu and colleagues at Fudan University published recent research findings in the December 2013 issue of the Journal of Gastrointestinal Surgery, the official periodical of the Society for Surgery of the Alimentary Tract. They reviewed the results of a number of potential serum […]